What's the ideal way to have a quest marker above an NPC or Quest giving event?

[Superspyi]

I'm using the quest marker graphics provided by @Xiphoid and I would like to have these animations above an NPC/event constantly looping but I am having issues with that.  Not sure where I need to go from here.  The closest solution I have is making a second event a tile or two above the quest provider but I'm not sure how to affect that event with results of the quest giver.  Basically what I'm trying to do is change the animation once a user has turned in the quest from the Gold ! to a grayed out !.

[Mcadams]

I made a tutorial for this some time ago. Not sure if it's the most efficient still but this is how I did it.

 

[Beefy Kasplant]

Have a different page in the event with the different graphic as an animation. 

 

This should help you: